Detalhe da pesquisa
1.
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Int J Mol Sci
; 25(2)2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279210
2.
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
Int J Mol Sci
; 24(6)2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982848
3.
New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.
Int J Mol Sci
; 24(11)2023 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298106
4.
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors.
Molecules
; 26(7)2021 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33808389
5.
Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments.
Molecules
; 26(11)2021 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34073771
6.
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
Int J Mol Sci
; 21(19)2020 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998385
7.
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.
Molecules
; 25(15)2020 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751997
8.
Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
Int J Mol Sci
; 21(1)2019 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31878088
9.
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
Molecules
; 24(20)2019 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31619021
10.
A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold.
Molecules
; 23(10)2018 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30261631
11.
Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure-activity relationship and molecular modeling study.
Steroids
; 165: 108771, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33221302
12.
Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments.
Anticancer Agents Med Chem
; 19(4): 463-472, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30523770